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epicardial adipose tissue heart failure life expectancy


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Increased myocardial dysfunction, dyssynchrony, and ...- epicardial adipose tissue heart failure life expectancy ,2014-8-3 · Increased life expectancy and decreased birth rates contribute to the notion of global population aging [1, 2], with cardiovascular disease (CVD) remaining the primary contributor to mortality [].A better understanding of the healthy aging-heart may support the early prevention, and thus reduced burden, of CVD.Epicardial adipose tissue and cardiovascular outcome in ...2017-12-1 · Variables that were entered into the model prior to elimination were: epicardial adipose tissue thickness, age, sex, nephropathy, atrial fibrillation, heart failure, prior stroke, peripheral artery disease, hypertension, hyperlipidaemia, diabetes, prior myocardial infarction, family history of coronary heart disease, numbers of affected ...



ACE2 Deficiency Worsens Epicardial Adipose Tissue ...

2015-7-29 · Obesity is a growing worldwide health problem and results in an increased health care burden and a decreased life expectancy. Obesity itself is an independent risk factor for the development of heart failure with preserved ejection fraction (HFPEF) independent of other comorbid conditions (1–4).Although a number of mechanisms are speculated to contribute to …

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Epicardial adipose tissue is related to arterial stiffness ...

2018-2-13 · Epicardial adipose tissue (EAT) is an emerging cardio-metabolic risk factor and has been shown to correlate with adverse cardiovascular (CV) outcome; however the underlying pathophysiology of this link is not well understood. The aim of this study was to evaluate the relationship between EAT and a comprehensive panel of cardiovascular risk biomarkers and …

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The roles of epicardial adipose tissue in heart failure ...

Heart failure is a growing health problem resulting in the decreased life expectancy of patients and severely increased the healthcare burden. The roles of epicardial adipose tissue in heart failure | springermedizin.de

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Pre-existing Health Conditions and Epicardial Adipose ...

Epicardial adipose tissue volume (EATV) has been used to evaluate the adipose tissue between the epicardial surface and pericardium, and reportedly associated with heart inflammation . In this multi-center, retrospective study, we explored the pre-existing health conditions and chest CT EATV as potential risk factors for myocardial injury in ...

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Pre-existing Health Conditions and Epicardial Adipose ...

Epicardial adipose tissue volume (EATV) has been used to evaluate the adipose tissue between the epicardial surface and pericardium, and reportedly associated with heart inflammation . In this multi-center, retrospective study, we explored the pre-existing health conditions and chest CT EATV as potential risk factors for myocardial injury in ...

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Changes in epicardial adipose tissue among women …

2022-2-1 · Epicardial adipose tissue as a metabolic transducer: role in heart failure and coronary artery disease Heart Fail. Rev. , 22 ( 2017 ) , pp. 889 - 902 , 10.1007/s10741-017-9644-1 View Record in Scopus Google Scholar

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Epicardial adipose tissue and cardiovascular diseases ...

2019-3-1 · Epicardial adipose tissue and heart failure EAT thickness is directly associated with left ventricular mass (LVM), independently of BMI [ 60 ]. Especially EAT accumulation around the right ventricle is associated with enlarged right ventricular mass in obese subjects, whereas other studies also focused of the relationship between EAT and ...

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Epicardial adipose tissue in obesity-related ... - Heart

2021-5-13 · Obesity is associated with the development of heart failure and is a major risk factor for heart failure with preserved ejection fraction (HFpEF). Epicardial adipose tissue (EAT) is a unique visceral fat in close proximity to the heart and is …

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Drugs That Ameliorate Epicardial Adipose Tissue ...

Heart failure with a preserved ejection fraction (HFpEF) and heart failure with a reduced ejection fraction (HFrEF) have distinctive pathophysiologies, and thus, therapeutic approaches to the 2 disorders should differ. Neurohormonal activation drives the progression of HFrEF, and neurohormonal antag …

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The roles of epicardial adipose tissue in heart failure

Heart failure is a growing health problem resulting in the decreased life expectancy of patients and severely increased the healthcare burden. Penetrating research on the pathogenesis and regulation mechanism of heart failure is important for treatment of …

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Proteomic analysis of epicardial and subcutaneous adipose ...

2010-7-1 · Proteomic differences between epicardial adipose tissue (EAT) and subcutaneous adipose tissue (SAT) in 11 patients undergoing cardiac surgery. Representative two-dimensional gel electrophoresis (2DE) gels ( top , first-dimension pI range, vertical scale molecular weight) showing the locations of spots with different intensities in EAT and SAT ...

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Epicardial adipose tissue in obesity-related ... - Heart

Obesity is associated with the development of heart failure and is a major risk factor for heart failure with preserved ejection fraction (HFpEF). Epicardial adipose tissue (EAT) is a unique visceral fat in close proximity to the heart and is of particular interest to the study of cardiac disease. Small poorly differentiated adipocytes with altered lipid:water content are associated …

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Adipocyte-derived factors suppress heart contraction ...

2010-6-22 · Similar to visceral adipose tissue, epicardial fat is a source of several inflammatory mediators, including TNF-α, IL-6, IL-1β, 30, 31 as well as …

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Epicardial adipose tissue is related to cardiac function ...

Background and aim Epicardial adipose tissue (EAT) is easily quantifiable visceral adipose tissue that is closely associated with cardiometabolic disease including heart failure with preserved left ventricular (LV) ejection fraction. As body fat distribution and metabolism are different between men and women, we evaluated the sex difference in ...

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Epicardial adipose tissue and cardiovascular outcome in ...

2017-12-1 · Variables that were entered into the model prior to elimination were: epicardial adipose tissue thickness, age, sex, nephropathy, atrial fibrillation, heart failure, prior stroke, peripheral artery disease, hypertension, hyperlipidaemia, diabetes, prior myocardial infarction, family history of coronary heart disease, numbers of affected ...

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Frontiers | Epicardial Fat Expansion in Diabetic and Obese ...

Epicardial adipose tissue (EAT)-related heart failure with preserved ejection fraction (HFpEF). Obesity and type 2 diabetes mellitus (T2DM) are common triggers of HFpEF, frequently associated with EAT expansion. EAT plays metabolic and mechanical roles in HFpEF development via para/vasocrine factors and pericardial restrain, respectively. Life ...

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:: IJHF :: International Journal of Heart Failure

Epicardial adipose tissue has been proposed as an important mediator that obesity exerts its effects on myocardial tissue in relation to systemic inflammation. 38) Under normal physiologic conditions, epicardial fat provides support and protection to myocardium, including serving as a mechanical cushion, producing heat, and releasing ...

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Proteomic analysis of epicardial and subcutaneous adipose ...

2010-7-1 · Proteomic differences between epicardial adipose tissue (EAT) and subcutaneous adipose tissue (SAT) in 11 patients undergoing cardiac surgery. Representative two-dimensional gel electrophoresis (2DE) gels ( top , first-dimension pI range, vertical scale molecular weight) showing the locations of spots with different intensities in EAT and SAT ...

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Epicardial adipose tissue as a mediator of cardiac ...

2022-1-7 · Epicardial adipose tissue (EAT) is a white visceral fat depot that uniquely exhibits BeAT features (21–23). Like BAT, EAT expresses UCP-1 and contains small multilocular adipocytes reflecting the transformation of WAT-derived precursor cells into mature thermogenic “brown-like” adipocytes .

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Gene pathway development in human epicardial adipose …

2016-8-18 · Cytoscape pathway analysis of the change in primary networks within epicardial adipose tissue (EAT) with age and schematic summary of changes in adipose tissue composition, structure, and primary regulatory pathways. Comparative subnetwork visualization for hub gene modular topology in ( A) neonates and ( B) infants.

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Increased Epicardial Adipose Tissue ... - Circulation Research

2016-2-29 · A, Norepinephrine and epinephrine determination by enzyme immunoassay in epicardial adipose tissue (EAT), subcutaneous adipose tissue (SCAT), and plasma of patients with heart failure. B , Quantification of tyrosine hydroxylase (TH), dopamine-β-hydroxylase (DBH), and phenylethanolamine N-methyltransferase (PNMT) mRNA levels by real-time ...

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Epicardial adipose tissue and cardiovascular diseases ...

2019-3-1 · Epicardial adipose tissue and heart failure EAT thickness is directly associated with left ventricular mass (LVM), independently of BMI [ 60 ]. Especially EAT accumulation around the right ventricle is associated with enlarged right ventricular mass in obese subjects, whereas other studies also focused of the relationship between EAT and ...

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Epicardial adipose tissue: anatomic, biomolecular and ...

Where present, epicardial and intra-abdominal fat evolve from brown adipose tissue during embryogenesis. 9 In the adult heart, fully differentiated white …

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Regulation of visceral and epicardial adipose tissue for ...

2017-4-4 · Nowadays, obesity is seriously increasing in most of the populations all over the world, and is associated with the development and progression of high-mortality diseases such as type-2 diabetes mellitus (T2DM) and its subsequent cardiovascular pathologies. Recent data suggest that both body fat distribution and adipocyte phenotype, can be more determinant for fatal …

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